Concentration and length dependence of DNA looping in transcriptional regulation.

In many cases, transcriptional regulation involves the binding of transcription factors at sites on the DNA that are not immediately adjacent to the promoter of interest. This action at a distance is often mediated by the formation of DNA loops: Binding at two or more sites on the DNA results in the...

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Bibliographic Details
Main Authors: Lin Han, Hernan G Garcia, Seth Blumberg, Kevin B Towles, John F Beausang, Philip C Nelson, Rob Phillips
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2682762?pdf=render