The functional interplay of low molecular weight thiols in Mycobacterium tuberculosis

The functional interplay of low molecular weight thiols in Mycobacterium tuberculosis

Abstract Background Three low molecular weight thiols are synthesized by Mycobacterium tuberculosis (M.tb), namely ergothioneine (ERG), mycothiol (MSH) and gamma-glutamylcysteine (GGC). They are able to counteract reactive oxygen species (ROS) and/or reactive nitrogen species (RNS). In addition, the...

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Bibliographic Details
Main Authors: C. Sao Emani, M. J. Williams, I. J. Wiid, B. Baker
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Biomedical Science
Subjects:
Thiols
Compensation
Tuberculosis
Therapeutic targets
ROS
RNS
Online Access:http://link.springer.com/article/10.1186/s12929-018-0458-9

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