Exosomes derived from mesenchymal stem cells improved core symptoms of genetically modified mouse model of autism Shank3B

Abstract Background Partial or an entire deletion of SHANK3 are considered as major drivers in the Phelan–McDermid syndrome, in which 75% of patients are diagnosed with autism spectrum disorder (ASD). During the recent years, there was an increasing interest in stem cell therapy in ASD, and specific...

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Bibliographic Details
Main Authors: N. Perets, O. Oron, S. Herman, E. Elliott, D. Offen
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Molecular Autism
Online Access:http://link.springer.com/article/10.1186/s13229-020-00366-x