Research progress on related genes for primary open angle glaucoma

Research progress on related genes for primary open angle glaucoma

Primary open angle glaucoma(POAG)is the main cause of blindness with visual field damage and optic nerve degeneration. In recent years, a lot of researches have been done, showing that genetic factors and gene mutation play an important role in POAG. There are more than 20 related POAG genes. Now we...

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Main Authors: Ailijiang·Aierken, Juerti·Hadier
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2014-04-01
Series:Guoji Yanke Zazhi
Subjects:
primary open angle glaucoma
gene mutation
heredity
research progress
Online Access:http://www.ies.net.cn/cn_publish/2014/4/201404020.pdf
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spelling doaj-0953237ce4ea4d71a69d71c3b925406c2020-11-24T22:55:08ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232014-04-0114465165310.3980/j.issn.1672-5123.2014.04.20Research progress on related genes for primary open angle glaucomaAilijiang·Aierken0Juerti·Hadier1Department of Ophthalmology, the First Affiliated Hospital of Xinjiang Medical University, Urumchi 830054, Xinjiang Uygur Autonomous Region, ChinaDepartment of Ophthalmology, the First Affiliated Hospital of Xinjiang Medical University, Urumchi 830054, Xinjiang Uygur Autonomous Region, ChinaPrimary open angle glaucoma(POAG)is the main cause of blindness with visual field damage and optic nerve degeneration. In recent years, a lot of researches have been done, showing that genetic factors and gene mutation play an important role in POAG. There are more than 20 related POAG genes. Now we will review the related genes of POAG, especially the well known causative genes of MYOC, OPTN, WDR36, and CAV1/CAV2, in terms of their locations, structures, research progress, <i>et al</i>, and provide a reference for genetic research in primary open-angle glaucoma.http://www.ies.net.cn/cn_publish/2014/4/201404020.pdfprimary open angle glaucomagene mutationheredityresearch progressresearch progress
collection DOAJ
language English
format Article
sources DOAJ
author Ailijiang·Aierken
Juerti·Hadier
spellingShingle Ailijiang·Aierken
Juerti·Hadier
Research progress on related genes for primary open angle glaucoma
Guoji Yanke Zazhi
primary open angle glaucoma
gene mutation
heredity
research progress
research progress
author_facet Ailijiang·Aierken
Juerti·Hadier
author_sort Ailijiang·Aierken
title Research progress on related genes for primary open angle glaucoma
title_short Research progress on related genes for primary open angle glaucoma
title_full Research progress on related genes for primary open angle glaucoma
title_fullStr Research progress on related genes for primary open angle glaucoma
title_full_unstemmed Research progress on related genes for primary open angle glaucoma
title_sort research progress on related genes for primary open angle glaucoma
publisher Press of International Journal of Ophthalmology (IJO PRESS)
series Guoji Yanke Zazhi
issn 1672-5123
1672-5123
publishDate 2014-04-01
description Primary open angle glaucoma(POAG)is the main cause of blindness with visual field damage and optic nerve degeneration. In recent years, a lot of researches have been done, showing that genetic factors and gene mutation play an important role in POAG. There are more than 20 related POAG genes. Now we will review the related genes of POAG, especially the well known causative genes of MYOC, OPTN, WDR36, and CAV1/CAV2, in terms of their locations, structures, research progress, <i>et al</i>, and provide a reference for genetic research in primary open-angle glaucoma.
topic primary open angle glaucoma
gene mutation
heredity
research progress
research progress
url http://www.ies.net.cn/cn_publish/2014/4/201404020.pdf
work_keys_str_mv AT ailijiangaierken researchprogressonrelatedgenesforprimaryopenangleglaucoma
AT juertihadier researchprogressonrelatedgenesforprimaryopenangleglaucoma
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