A Point Mutation in Suppressor of Cytokine Signalling 2 (Socs2) Increases the Susceptibility to Inflammation of the Mammary Gland while Associated with Higher Body Weight and Size and Higher Milk Production in a Sheep Model.

A Point Mutation in Suppressor of Cytokine Signalling 2 (Socs2) Increases the Susceptibility to Inflammation of the Mammary Gland while Associated with Higher Body Weight and Size and Higher Milk Production in a Sheep Model.

Mastitis is an infectious disease mainly caused by bacteria invading the mammary gland. Genetic control of susceptibility to mastitis has been widely evidenced in dairy ruminants, but the genetic basis and underlying mechanisms are still largely unknown. We describe the discovery, fine mapping and f...

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Bibliographic Details
Main Authors: Rachel Rupp, Pavel Senin, Julien Sarry, Charlotte Allain, Christian Tasca, Laeticia Ligat, David Portes, Florent Woloszyn, Olivier Bouchez, Guillaume Tabouret, Mathieu Lebastard, Cécile Caubet, Gilles Foucras, Gwenola Tosser-Klopp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4676722?pdf=render

Internet

http://europepmc.org/articles/PMC4676722?pdf=render

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