Measuring the Inducible, Replication-Competent HIV Reservoir Using an Ultra-Sensitive p24 Readout, the Digital ELISA Viral Outgrowth Assay

Measuring the Inducible, Replication-Competent HIV Reservoir Using an Ultra-Sensitive p24 Readout, the Digital ELISA Viral Outgrowth Assay

Quantifying the inducible HIV reservoir provides an estimate of the frequency of quiescent HIV-infected cells in humans as well as in animal models, and can help ascertain the efficacy of latency reversing agents (LRAs). The quantitative viral outgrowth assay (QVOA) is used to measure inducible, rep...

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Bibliographic Details
Main Authors: Erin L. Stuelke, Katherine S. James, Jennifer L. Kirchherr, Brigitte Allard, Caroline Baker, Joann D. Kuruc, Cindy L. Gay, David M. Margolis, Nancie M. Archin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
QVOA
DEVO
HIV
outgrowth
IUPM
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01971/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01971/full

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