Comparison of line probe assay to BACTEC MGIT 960 system for susceptibility testing of first and second-line anti-tuberculosis drugs in a referral laboratory in South Africa

Comparison of line probe assay to BACTEC MGIT 960 system for susceptibility testing of first and second-line anti-tuberculosis drugs in a referral laboratory in South Africa

Abstract Background The incidence of multidrug-resistant tuberculosis (MDR-TB) is increasing and the emergence of extensively drug-resistant tuberculosis (XDR-TB) is a major challenge. Controlling resistance, reducing transmission and improving treatment outcomes in MDR/XDR-TB patients is reliant on...

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Bibliographic Details
Main Authors: Nontuthuko E. Maningi, Lesibana A. Malinga, John F. Antiabong, Ruth M. Lekalakala, Nontombi M. Mbelle
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Infectious Diseases
Subjects:
Drug-resistance
Mycobacterium tuberculosis
Line-probe assay
MGIT 960 system
Isoniazid
Rifampicin
Online Access:http://link.springer.com/article/10.1186/s12879-017-2898-3

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