EL_PSSM-RT: DNA-binding residue prediction by integrating ensemble learning with PSSM Relation Transformation

EL_PSSM-RT: DNA-binding residue prediction by integrating ensemble learning with PSSM Relation Transformation

Abstract Background Prediction of DNA-binding residue is important for understanding the protein-DNA recognition mechanism. Many computational methods have been proposed for the prediction, but most of them do not consider the relationships of evolutionary information between residues. Results In th...

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Bibliographic Details
Main Authors: Jiyun Zhou, Qin Lu, Ruifeng Xu, Yulan He, Hongpeng Wang
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Bioinformatics
Subjects:
DNA-protein interaction
DNA-binding residue
PSSM
Ensemble learning
SVM
Random forest
Online Access:http://link.springer.com/article/10.1186/s12859-017-1792-8

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