Presenilins are required for maintenance of neural stem cells in the developing brain
<p>Abstract</p> <p>The early embryonic lethality of mutant mice bearing germ-line deletions of both <it>presenilin </it>genes precluded the study of their functions in neural development. We therefore employed the Cre-loxP technology to generate <it>presenilin <...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-01-01
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| Series: | Molecular Neurodegeneration |
| Online Access: | http://www.molecularneurodegeneration.com/content/3/1/2 |