New and Old Genes Associated with Primary and Established Responses to Paclitaxel Treatment in Ovarian Cancer Cell Lines

Development of drug resistance is the main reason for low chemotherapy effectiveness in treating ovarian cancer. Paclitaxel (PAC) is a chemotherapeutic drug used in the treatment of this cancer. We analysed the development of PAC resistance in two ovarian cancer cell lines. Exposure of drug-sensitiv...

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Bibliographic Details
Main Authors: Monika Świerczewska, Andrzej Klejewski, Maciej Brązert, Dominika Kaźmierczak, Dariusz Iżycki, Michał Nowicki, Maciej Zabel, Radosław Januchowski
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/4/891