Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery
Treatment for eye injuries and diseases is most efficient when delivered directly into the eye. Here, the authors developed a patient-friendly eye patch equipped with an array of detachable microneedles, through which drugs can be delivered through the cornea for an extended period of time.
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Nature Publishing Group
2018-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-06981-w |
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doaj-090f704a9c5d447980ebbee38cf8315f2021-05-11T10:12:46ZengNature Publishing GroupNature Communications2041-17232018-11-019111210.1038/s41467-018-06981-wSelf-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug deliveryAung Than0Chenghao Liu1Hao Chang2Phan Khanh Duong3Chui Ming Gemmy Cheung4Chenjie Xu5Xiaomeng Wang6Peng Chen7School of Chemical and Biomedical Engineering, Nanyang Technological UniversityLee Kong Chian School of Medicine, Nanyang Technological UniversitySchool of Chemical and Biomedical Engineering, Nanyang Technological UniversitySchool of Chemical and Biomedical Engineering, Nanyang Technological UniversitySingapore National Eye CentreSchool of Chemical and Biomedical Engineering, Nanyang Technological UniversityLee Kong Chian School of Medicine, Nanyang Technological UniversitySchool of Chemical and Biomedical Engineering, Nanyang Technological UniversityTreatment for eye injuries and diseases is most efficient when delivered directly into the eye. Here, the authors developed a patient-friendly eye patch equipped with an array of detachable microneedles, through which drugs can be delivered through the cornea for an extended period of time.https://doi.org/10.1038/s41467-018-06981-w |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Aung Than Chenghao Liu Hao Chang Phan Khanh Duong Chui Ming Gemmy Cheung Chenjie Xu Xiaomeng Wang Peng Chen |
spellingShingle |
Aung Than Chenghao Liu Hao Chang Phan Khanh Duong Chui Ming Gemmy Cheung Chenjie Xu Xiaomeng Wang Peng Chen Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery Nature Communications |
author_facet |
Aung Than Chenghao Liu Hao Chang Phan Khanh Duong Chui Ming Gemmy Cheung Chenjie Xu Xiaomeng Wang Peng Chen |
author_sort |
Aung Than |
title |
Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery |
title_short |
Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery |
title_full |
Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery |
title_fullStr |
Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery |
title_full_unstemmed |
Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery |
title_sort |
self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2018-11-01 |
description |
Treatment for eye injuries and diseases is most efficient when delivered directly into the eye. Here, the authors developed a patient-friendly eye patch equipped with an array of detachable microneedles, through which drugs can be delivered through the cornea for an extended period of time. |
url |
https://doi.org/10.1038/s41467-018-06981-w |
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