Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery

Treatment for eye injuries and diseases is most efficient when delivered directly into the eye. Here, the authors developed a patient-friendly eye patch equipped with an array of detachable microneedles, through which drugs can be delivered through the cornea for an extended period of time.

Bibliographic Details
Main Authors: Aung Than, Chenghao Liu, Hao Chang, Phan Khanh Duong, Chui Ming Gemmy Cheung, Chenjie Xu, Xiaomeng Wang, Peng Chen
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06981-w
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spelling doaj-090f704a9c5d447980ebbee38cf8315f2021-05-11T10:12:46ZengNature Publishing GroupNature Communications2041-17232018-11-019111210.1038/s41467-018-06981-wSelf-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug deliveryAung Than0Chenghao Liu1Hao Chang2Phan Khanh Duong3Chui Ming Gemmy Cheung4Chenjie Xu5Xiaomeng Wang6Peng Chen7School of Chemical and Biomedical Engineering, Nanyang Technological UniversityLee Kong Chian School of Medicine, Nanyang Technological UniversitySchool of Chemical and Biomedical Engineering, Nanyang Technological UniversitySchool of Chemical and Biomedical Engineering, Nanyang Technological UniversitySingapore National Eye CentreSchool of Chemical and Biomedical Engineering, Nanyang Technological UniversityLee Kong Chian School of Medicine, Nanyang Technological UniversitySchool of Chemical and Biomedical Engineering, Nanyang Technological UniversityTreatment for eye injuries and diseases is most efficient when delivered directly into the eye. Here, the authors developed a patient-friendly eye patch equipped with an array of detachable microneedles, through which drugs can be delivered through the cornea for an extended period of time.https://doi.org/10.1038/s41467-018-06981-w
collection DOAJ
language English
format Article
sources DOAJ
author Aung Than
Chenghao Liu
Hao Chang
Phan Khanh Duong
Chui Ming Gemmy Cheung
Chenjie Xu
Xiaomeng Wang
Peng Chen
spellingShingle Aung Than
Chenghao Liu
Hao Chang
Phan Khanh Duong
Chui Ming Gemmy Cheung
Chenjie Xu
Xiaomeng Wang
Peng Chen
Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery
Nature Communications
author_facet Aung Than
Chenghao Liu
Hao Chang
Phan Khanh Duong
Chui Ming Gemmy Cheung
Chenjie Xu
Xiaomeng Wang
Peng Chen
author_sort Aung Than
title Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery
title_short Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery
title_full Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery
title_fullStr Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery
title_full_unstemmed Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery
title_sort self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2018-11-01
description Treatment for eye injuries and diseases is most efficient when delivered directly into the eye. Here, the authors developed a patient-friendly eye patch equipped with an array of detachable microneedles, through which drugs can be delivered through the cornea for an extended period of time.
url https://doi.org/10.1038/s41467-018-06981-w
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