Reversed phase parallel artificial membrane permeation assay for log P measurement

A reversed phase parallel artificial membrane permeation assay (RP-PAMPA) was newly invented for log P measurement. An oil/water/oil sandwich was constructed using a conventional PAMPA instrument. 1 % agarose was used to improve the physical stability of the water phase. A linear correlation between...

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Bibliographic Details
Main Authors: Zihao Song, Katsuhide Terada, Kiyohiko Sugano
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2016-03-01
Series:ADMET and DMPK
Online Access:http://pub.iapchem.org/ojs/index.php/admet/article/view/277

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