Recombinant deoxyribonucleoside kinase from Drosophila melanogaster can improve gemcitabine based combined gene/chemotherapy for targeting cancer cells

Recombinant deoxyribonucleoside kinase from Drosophila melanogaster can improve gemcitabine based combined gene/chemotherapy for targeting cancer cells

A recombinant deoxyribonucleoside kinase from Drosophila melanogaster with a deletion of the last 20 amino acid residues (named DmdNKΔC20) was hypothesized as a potential therapeutic tool for gene therapy due to its broad substrate specificity and better catalytic efficiency towards nucleosides and...

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Bibliographic Details
Main Authors: Mahak Fatima, M. Mubasshar Iqbal Ahmed, Faiza Batool, Anjum Riaz, Moazzam Ali, Birgitte Munch-Petersen, Zeeshan Mutahir
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2019-03-01
Series:Bosnian Journal of Basic Medical Sciences
Subjects:
Drosophila melanogaster deoxyribonucleoside kinase
Suicide gene therapy
Breast cancer
Drug resistance
Gemcitabine
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/4136

Internet

https://www.bjbms.org/ojs/index.php/bjbms/article/view/4136

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