Inhibitory Effects of Some Philippine Medicinal Plants on Germ Cell Genotoxicity of Methylmethansulfonate, Tetracycline, and Chloromycetin

• Main Authors: Clara Lim-Sylianco, F. R. Blanco
• Format: Article
• Language: English
• Published: University of the Philippines 1990-12-01
• Series: Science Diliman
• Subjects: Methylmethansulfonate; tetracyline; chloromycetin; germ cell; Philippine medicinal plants
• Online Access: http://journals.upd.edu.ph/index.php/sciencediliman/article/view/285
• ISSN: 0115-7809; 2012-0818

Methylmethansulfonate, tetracyline, and chloromycetin were shown to be genetoxic to germ cell. These genotoxins induced reduction in fertility index, gestation index, and implantation index. The percentage dead implants and percentage of females with resorptions were increased.Decoctions from bayabas, kalatsutsi, kamias, kogon, makabuhay, malunggay, mayana, sambong, tanglad, and ulasimang bato increased fertility index, gestation index, implantation index, and reduced percentage dead implants and percentage of female with resorption.