Lymphocyte expansion in bioreactors: upgrading adoptive cell therapy

Abstract Bioreactors are essential tools for the development of efficient and high-quality cell therapy products. However, their application is far from full potential, holding several challenges when reconciling the complex biology of the cells to be expanded with the need for a manufacturing proce...

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Bibliographic Details
Main Authors: Oscar Fabian Garcia-Aponte, Christoph Herwig, Bence Kozma
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Biological Engineering
Subjects:
Online Access:https://doi.org/10.1186/s13036-021-00264-7