Relation of bleeding patterns and factor VIII levels in children with hemophilia
Background The high costs of factor VIII examination cause the delay in the diagnosis of hemophilia A; consequently many pa- tients do not receive adequate therapy which results in failure to survive into adulthood or survive with creeple. Objective To determine bleeding patterns of hemophilia A pa-...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Indonesian Pediatric Society Publishing House
2016-10-01
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| Series: | Paediatrica Indonesiana |
| Subjects: | |
| Online Access: | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/921 |
| Summary: | Background The high costs of factor VIII examination cause the
delay in the diagnosis of hemophilia A; consequently many pa-
tients do not receive adequate therapy which results in failure to
survive into adulthood or survive with creeple.
Objective To determine bleeding patterns of hemophilia A pa-
tients for the prediction of its classification.
Methods We perform retrospective analysis of hemophilia patients
at the Integrated Service Center of Hemophilia, Cipto Mangun-
kusumo Hospital, Jakarta.
Results Family history, age at the first bleeding, frequency of bleed-
ing, and factor VIII examination can significantly differentiate the
classification of hemophilia A (P=0.015; 0.014; <0.0001; and
<0.0001, respectively) while age groups, triggering trauma for the
first bleeding, type of the first bleeding, history of previous trauma,
the most frequent type of bleeding, age at diagnosis, and con-
sumption of cryoprecipitate cannot. (P=0.985; 0.475; 0.342; 0.318;
0.058; 0.477; and 0.547, respectively).
Conclusion Age at first bleeding, frequency of bleeding, and fam-
ily history can be used to predict classification of hemophilia A. |
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| ISSN: | 0030-9311 2338-476X |