Folic acid protects against lipopolysaccharide-induced preterm delivery and intrauterine growth restriction through its anti-inflammatory effect in mice.

Increasing evidence demonstrates that maternal folic acid (FA) supplementation during pregnancy reduces the risk of neural tube defects, but whether FA prevents preterm delivery and intrauterine growth restriction (IUGR) remains obscure. Previous studies showed that maternal lipopolysaccharide (LPS)...

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Bibliographic Details
Main Authors: Mei Zhao, Yuan-Hua Chen, Xu-Ting Dong, Jun Zhou, Xue Chen, Hua Wang, Shu-Xian Wu, Mi-Zhen Xia, Cheng Zhang, De-Xiang Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3855776?pdf=render