Hereditary Angioedema Type II: First Presentation in Adulthood with Recurrent Severe Abdominal Pain

Hereditary Angioedema Type II: First Presentation in Adulthood with Recurrent Severe Abdominal Pain

A 27-year-old Emirate man presented to Cleveland Clinic Abu Dhabi emergency department with a 4 year history of recurrent episodes of severe swellings affecting different parts of his body. He used to get 2 swelling episodes every week affecting either his face, hands, feet or scrotum and severe abd...

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Main Authors: Mohamed Abuzakouk, Nada AlMahmeed, Esat Memisoglu, Martine McManus, Aydamir Alrakawi
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Case Reports in Immunology
Online Access:http://dx.doi.org/10.1155/2018/7435870
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spelling doaj-08c6d8341a1443c8bbbcb76cd1f2f51e2020-11-25T00:16:19ZengHindawi LimitedCase Reports in Immunology2090-66092090-66172018-01-01201810.1155/2018/74358707435870Hereditary Angioedema Type II: First Presentation in Adulthood with Recurrent Severe Abdominal PainMohamed Abuzakouk0Nada AlMahmeed1Esat Memisoglu2Martine McManus3Aydamir Alrakawi4Cleveland Clinic Abu Dhabi, UAECleveland Clinic Abu Dhabi, UAECleveland Clinic Abu Dhabi, UAECleveland Clinic Abu Dhabi, UAECleveland Clinic Abu Dhabi, UAEA 27-year-old Emirate man presented to Cleveland Clinic Abu Dhabi emergency department with a 4 year history of recurrent episodes of severe swellings affecting different parts of his body. He used to get 2 swelling episodes every week affecting either his face, hands, feet or scrotum and severe abdominal pain twice a week. Abdominal CT scan and a colonoscopy showed bowel wall oedema. There was no family history of similar complaint or of hereditary angioedema (HAE). Complement studies confirmed the diagnosis of HAE type II. He was commenced on danazol 100 mg twice daily and his symptoms resolved. This case report highlights the importance of considering HAE in patients with recurrent unexplained abdominal pain even in the absence of positive family history of HAE.http://dx.doi.org/10.1155/2018/7435870
collection DOAJ
language English
format Article
sources DOAJ
author Mohamed Abuzakouk
Nada AlMahmeed
Esat Memisoglu
Martine McManus
Aydamir Alrakawi
spellingShingle Mohamed Abuzakouk
Nada AlMahmeed
Esat Memisoglu
Martine McManus
Aydamir Alrakawi
Hereditary Angioedema Type II: First Presentation in Adulthood with Recurrent Severe Abdominal Pain
Case Reports in Immunology
author_facet Mohamed Abuzakouk
Nada AlMahmeed
Esat Memisoglu
Martine McManus
Aydamir Alrakawi
author_sort Mohamed Abuzakouk
title Hereditary Angioedema Type II: First Presentation in Adulthood with Recurrent Severe Abdominal Pain
title_short Hereditary Angioedema Type II: First Presentation in Adulthood with Recurrent Severe Abdominal Pain
title_full Hereditary Angioedema Type II: First Presentation in Adulthood with Recurrent Severe Abdominal Pain
title_fullStr Hereditary Angioedema Type II: First Presentation in Adulthood with Recurrent Severe Abdominal Pain
title_full_unstemmed Hereditary Angioedema Type II: First Presentation in Adulthood with Recurrent Severe Abdominal Pain
title_sort hereditary angioedema type ii: first presentation in adulthood with recurrent severe abdominal pain
publisher Hindawi Limited
series Case Reports in Immunology
issn 2090-6609
2090-6617
publishDate 2018-01-01
description A 27-year-old Emirate man presented to Cleveland Clinic Abu Dhabi emergency department with a 4 year history of recurrent episodes of severe swellings affecting different parts of his body. He used to get 2 swelling episodes every week affecting either his face, hands, feet or scrotum and severe abdominal pain twice a week. Abdominal CT scan and a colonoscopy showed bowel wall oedema. There was no family history of similar complaint or of hereditary angioedema (HAE). Complement studies confirmed the diagnosis of HAE type II. He was commenced on danazol 100 mg twice daily and his symptoms resolved. This case report highlights the importance of considering HAE in patients with recurrent unexplained abdominal pain even in the absence of positive family history of HAE.
url http://dx.doi.org/10.1155/2018/7435870
work_keys_str_mv AT mohamedabuzakouk hereditaryangioedematypeiifirstpresentationinadulthoodwithrecurrentsevereabdominalpain
AT nadaalmahmeed hereditaryangioedematypeiifirstpresentationinadulthoodwithrecurrentsevereabdominalpain
AT esatmemisoglu hereditaryangioedematypeiifirstpresentationinadulthoodwithrecurrentsevereabdominalpain
AT martinemcmanus hereditaryangioedematypeiifirstpresentationinadulthoodwithrecurrentsevereabdominalpain
AT aydamiralrakawi hereditaryangioedematypeiifirstpresentationinadulthoodwithrecurrentsevereabdominalpain
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