Identifying significantly impacted pathways: a comprehensive review and assessment
Abstract Background Many high-throughput experiments compare two phenotypes such as disease vs. healthy, with the goal of understanding the underlying biological phenomena characterizing the given phenotype. Because of the importance of this type of analysis, more than 70 pathway analysis methods ha...
Main Authors: | Tuan-Minh Nguyen, Adib Shafi, Tin Nguyen, Sorin Draghici |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-10-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13059-019-1790-4 |
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