The Protective Role of Immunomodulators on Tissue-Type Plasminogen Activator-Induced Hemorrhagic Transformation in Experimental Stroke: A Systematic Review and Meta-Analysis

The Protective Role of Immunomodulators on Tissue-Type Plasminogen Activator-Induced Hemorrhagic Transformation in Experimental Stroke: A Systematic Review and Meta-Analysis

Background: Recanalization with tissue plasminogen activator (tPA) is the only approved agent available for acute ischemic stroke. But delayed treatment of tPA may lead to lethal intracerebral hemorrhagic transformation (HT). Numerous studies have reported that immunomodulators have good efficacy on...

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Bibliographic Details
Main Authors:	Yang Ye, Yu-Tian Zhu, Hong-Xuan Tong, Jing-Yan Han
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-12-01
Series:	Frontiers in Pharmacology
Subjects:	tissue-type plasminogen activator stroke meta-analysis immunomodulator hemorrhagic transformation animal model
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2020.615166/full

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