Tumorigenic Effects of Tamoxifen on the Female Genital Tract

Tamoxifen is widely used for endocrine treatment and breast cancer prevention. It acts as both an estrogen antagonist in breast tissue and an estrogen agonist in the female lower genital tract. Tamoxifen causes severe gynecologic side effects, such as endometrial cancer. This review focuses on the e...

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Bibliographic Details
Main Authors: Kaei Nasu M.D., Ph.D., Noriyuki Takai, Masakazu Nishida, Hisashi Narahara
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Clinical Medicine Insights: Pathology
Online Access:https://doi.org/10.4137/CPath.S487