CK2 Secreted by Leishmania braziliensis Mediates Macrophage Association Invasion: A Comparative Study between Virulent and Avirulent Promastigotes

CK2 Secreted by Leishmania braziliensis Mediates Macrophage Association Invasion: A Comparative Study between Virulent and Avirulent Promastigotes

CK2 is a protein kinase distributed in different compartments of Leishmania braziliensis: an externally oriented ecto-CK2, an intracellular CK2, and a secreted CK2. This latter form is constitutively secreted from the parasite (CsCK2), but such secretion may be highly enhanced by the association of...

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Bibliographic Details
Main Authors:	Ana Madeira Brito Zylbersztejn, Carlos Gustavo Vieira de Morais, Ana Karina Castro Lima, Joyce Eliza de Oliveira Souza, Angela Hampshire Lopes, Sílvia Amaral Gonçalves Da-Silva, Mário Alberto Cardoso Silva-Neto, Patrícia Maria Lourenço Dutra
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2015/167323

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