Immunogenicity of a Tripartite Cell Penetrating Peptide Containing a MUC1 Variable Number of Tandem Repeat (VNTR) and A T Helper Epitope

Immunogenicity of a Tripartite Cell Penetrating Peptide Containing a MUC1 Variable Number of Tandem Repeat (VNTR) and A T Helper Epitope

Peptide-based vaccines for cancer have many advantages however, for optimization these immunogens should incorporate peptide epitopes that induce CD8, as well as CD4 responses, antibody and long term immunity. Cell penetrating peptides (CPP) with a capacity of cytosolic delivery have been used to de...

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Bibliographic Details
Main Authors: Nicole Brooks, Jennifer Hsu, Sandra Esparon, Dodie Pouniotis, Geoffrey A. Pietersz
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Molecules
Subjects:
penetratin
membrane translocating peptide
membrane penetrating peptide
vaccine
Mucin 1
immunogenicity
antigen delivery
immunotherapy
multiple antigen peptide
TLR agonist
Online Access:http://www.mdpi.com/1420-3049/23/9/2233

Internet

http://www.mdpi.com/1420-3049/23/9/2233

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