Dramatic improvement in dissolution rate of albendazole by a simple, one-step, industrially scalable technique

Dramatic improvement in dissolution rate of albendazole by a simple, one-step, industrially scalable technique

Low solubility and dissolution rate are the primary challenges in the drug development which substantially impact the oral absorption and bioavailability of drugs. Due to the poor water solubility, Albendazole (ABZ) is poorly absorbed from the gastrointestinal tract and shows low oral bioavailabilit...

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Bibliographic Details
Main Authors: Saeed Ghanbarzadeh, Aram Khalili, Abolghasem Jouyban, Shahram Emami, Yousef Javadzadeh, Mohammad Solhi, Hamed Hamishehkar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
albendazole; spray drying; dissolution rate; solubility; surfactants
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2016;volume=11;issue=6;spage=435;epage=444;aulast=Ghanbarzadeh

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http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2016;volume=11;issue=6;spage=435;epage=444;aulast=Ghanbarzadeh

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