Cisplatin and beyond: molecular mechanisms of action and drug resistance development in cancer chemotherapy
Platinum-based anticancer drugs are widely used in the chemotherapy of human neoplasms. The major obstacle for the clinical use of this class of drugs is the development of resistance and toxicity. It is therefore very important to understand the chemical properties, transport and metabolic pathways...
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Format: | Article |
Language: | English |
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Sciendo
2019-03-01
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Series: | Radiology and Oncology |
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Online Access: | https://doi.org/10.2478/raon-2019-0018 |