Cisplatin and beyond: molecular mechanisms of action and drug resistance development in cancer chemotherapy

Platinum-based anticancer drugs are widely used in the chemotherapy of human neoplasms. The major obstacle for the clinical use of this class of drugs is the development of resistance and toxicity. It is therefore very important to understand the chemical properties, transport and metabolic pathways...

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Bibliographic Details
Main Author: Makovec Tomaz
Format: Article
Language:English
Published: Sciendo 2019-03-01
Series:Radiology and Oncology
Subjects:
Online Access:https://doi.org/10.2478/raon-2019-0018