Dkk1 inhibits malignant transformation induced by Bmi1 via the β‐catenin signaling axis in WB‐F344 oval cells

Dkk1 inhibits malignant transformation induced by Bmi1 via the β‐catenin signaling axis in WB‐F344 oval cells

Dickkopf‐1 (Dkk1) is an inhibitor of Wnt signaling involved in cancer cell proliferation, apoptosis, and migration and angiogenesis. It was previously reported that B cell‐specific Moloney mouse leukemia virus integration site 1 (Bmi1) activates the Wnt pathway by inhibiting the expression of DKK1 i...

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Bibliographic Details
Main Authors: Jinjun Ye, Le Xin, Jidong Liu, Tao Tang, Xing Bao, Yukuang Yan
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:FEBS Open Bio
Subjects:
Bmi1
Dkk1
hepatocellular carcinoma
malignant transformation
WB‐F344 oval cell
β‐catenin
Online Access:https://doi.org/10.1002/2211-5463.13132

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