Peripheral surgical wounding and age-dependent neuroinflammation in mice.

Post-operative cognitive dysfunction is associated with morbidity and mortality. However, its neuropathogenesis remains largely to be determined. Neuroinflammation and accumulation of β-amyloid (Aβ) have been reported to contribute to cognitive dysfunction in humans and cognitive impairment in anima...

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Bibliographic Details
Main Authors: Zhipeng Xu, Yuanlin Dong, Hui Wang, Deborah J Culley, Edward R Marcantonio, Gregory Crosby, Rudolph E Tanzi, Yiying Zhang, Zhongcong Xie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24796537/pdf/?tool=EBI