A Heterotypic Tridimensional Model to Study the Interaction of Macrophages and Glioblastoma In Vitro

A Heterotypic Tridimensional Model to Study the Interaction of Macrophages and Glioblastoma In Vitro

Background: Glioblastoma multiforme (GBM) is the most frequent and aggressive primary brain tumor, and macrophages account for 30–40% of its composition. Most of these macrophages derive from bone marrow monocytes playing a crucial role in tumor progression. Unraveling the mechanisms of macrophages-...

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Bibliographic Details
Main Authors: María José Gattas, Ivana Gisele Estecho, María Amparo Lago Huvelle, Andrea Emilse Errasti, Eugenio Antonio Carrera Silva, Marina Simian
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
glioblastoma multiforme
monocytes
macrophage polarization
3D cultures
tumor-stromal interactions
CD206
Online Access:https://www.mdpi.com/1422-0067/22/10/5105

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