Tetrahydrocannabinol Reduces Hapten-Driven Mast Cell Accumulation and Persistent Tactile Sensitivity in Mouse Model of Allergen-Provoked Localized Vulvodynia

Tetrahydrocannabinol Reduces Hapten-Driven Mast Cell Accumulation and Persistent Tactile Sensitivity in Mouse Model of Allergen-Provoked Localized Vulvodynia

Vulvodynia is a remarkably prevalent chronic pain condition of unknown etiology. An increase in numbers of vulvar mast cells often accompanies a clinical diagnosis of vulvodynia and a history of allergies amplifies the risk of developing this condition. We previously showed that repeated exposures t...

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Bibliographic Details
Main Authors: Beebie Boo, Rohit Kamath, Erica Arriaga-Gomez, Jasmine Landry, Elizabeth Emanuel, Sookyong Joo, Marietta Saldías Montivero, Tijana Martinov, Brian T. Fife, Devavani Chatterjea
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
mast cells
dinitrofluorobenzene
hypersensitivity
chronic pain
vulvodynia
Δ<sup>9</sup>-tetrahydrocannabinol
Online Access:https://www.mdpi.com/1422-0067/20/9/2163

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