MicroRNAs miR-17 and miR-20a inhibit T cell activation genes and are under-expressed in MS whole blood.

MicroRNAs miR-17 and miR-20a inhibit T cell activation genes and are under-expressed in MS whole blood.

It is well established that Multiple Sclerosis (MS) is an immune mediated disease. Little is known about what drives the differential control of the immune system in MS patients compared to unaffected individuals. MicroRNAs (miRNAs) are small non-coding nucleic acids that are involved in the control...

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Bibliographic Details
Main Authors: Mathew B Cox, Murray J Cairns, Kaushal S Gandhi, Adam P Carroll, Sophia Moscovis, Graeme J Stewart, Simon Broadley, Rodney J Scott, David R Booth, Jeannette Lechner-Scott, ANZgene Multiple Sclerosis Genetics Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2920328?pdf=render

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