The high-risk HPV infection and urinary system tumor

HPV is classified into high-risk and low-risk types depending on its probability of leading to tumorigenesis. Many studies have shown that HPV infection, especially the infection caused by the high-risk type, is always related to prostate cancer, bladder cancer, penile cancer, testicular cancer, and...

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Main Author:	Yang Wenyan
Format:	Article
Language:	English
Published:	Sciendo 2018-04-01
Series:	Infection International
Subjects:	HPV prostate cancer bladder cancer penile cancer testicular cancer
Online Access:	http://www.degruyter.com/view/j/ii.2017.6.issue-4/ii-2018-0004/ii-2018-0004.xml?format=INT

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spelling	doaj-08345376118d43118cb31a4791e5221f2020-11-24T22:10:52ZengSciendoInfection International2544-03492018-04-016410811110.2478/ii-2018-0004ii-2018-0004The high-risk HPV infection and urinary system tumorYang Wenyan0Department of Medical Information, Shandong Academy of Medical Sciences, Jinan250001, ChinaHPV is classified into high-risk and low-risk types depending on its probability of leading to tumorigenesis. Many studies have shown that HPV infection, especially the infection caused by the high-risk type, is always related to prostate cancer, bladder cancer, penile cancer, testicular cancer, and other urinary system tumors. However, previous studies differed in sexual openness and racial genetic susceptibility of the study object, sample size, and experimental methods. Hence, the correlation between high-risk HPV infection and urinary system tumors remains controversial. The early open reading frame of the HPV genome is composed of E1–E7, among which E6 and E7 are the key transfer proteins. The combination of these proteins with oncogene and anti-oncogene may be one of the mechanisms leading to tumorigenesis.http://www.degruyter.com/view/j/ii.2017.6.issue-4/ii-2018-0004/ii-2018-0004.xml?format=INTHPVprostate cancerbladder cancerpenile cancertesticular cancer
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Yang Wenyan
spellingShingle	Yang Wenyan The high-risk HPV infection and urinary system tumor Infection International HPV prostate cancer bladder cancer penile cancer testicular cancer
author_facet	Yang Wenyan
author_sort	Yang Wenyan
title	The high-risk HPV infection and urinary system tumor
title_short	The high-risk HPV infection and urinary system tumor
title_full	The high-risk HPV infection and urinary system tumor
title_fullStr	The high-risk HPV infection and urinary system tumor
title_full_unstemmed	The high-risk HPV infection and urinary system tumor
title_sort	high-risk hpv infection and urinary system tumor
publisher	Sciendo
series	Infection International
issn	2544-0349
publishDate	2018-04-01
description	HPV is classified into high-risk and low-risk types depending on its probability of leading to tumorigenesis. Many studies have shown that HPV infection, especially the infection caused by the high-risk type, is always related to prostate cancer, bladder cancer, penile cancer, testicular cancer, and other urinary system tumors. However, previous studies differed in sexual openness and racial genetic susceptibility of the study object, sample size, and experimental methods. Hence, the correlation between high-risk HPV infection and urinary system tumors remains controversial. The early open reading frame of the HPV genome is composed of E1–E7, among which E6 and E7 are the key transfer proteins. The combination of these proteins with oncogene and anti-oncogene may be one of the mechanisms leading to tumorigenesis.
topic	HPV prostate cancer bladder cancer penile cancer testicular cancer
url	http://www.degruyter.com/view/j/ii.2017.6.issue-4/ii-2018-0004/ii-2018-0004.xml?format=INT
work_keys_str_mv	AT yangwenyan thehighriskhpvinfectionandurinarysystemtumor AT yangwenyan highriskhpvinfectionandurinarysystemtumor
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The high-risk HPV infection and urinary system tumor

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