Platelet-derived growth factor (PDGF)-BB-mediated induction of monocyte chemoattractant protein 1 in human astrocytes: implications for HIV-associated neuroinflammation

Platelet-derived growth factor (PDGF)-BB-mediated induction of monocyte chemoattractant protein 1 in human astrocytes: implications for HIV-associated neuroinflammation

<p>Abstract</p> <p>Chemokine (C-C motif) ligand 2, also known as monocyte chemoattractant protein 1 (MCP-1) is an important factor for the pathogenesis of HIV-associated neurocognitive disorders (HAND). The mechanisms of MCP-1-mediated neuropathogenesis, in part, revolve around its...

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Bibliographic Details
Main Authors: Bethel-Brown Crystal, Yao Honghong, Hu Guoku, Buch Shilpa
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/9/1/262

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