Factors Influencing Clinical Pregnancy Rates After Myomectomy Among Infertile Women: A Single Center Retrospective Study

• Main Authors: Meryem Kuru Pekcan, Esra İşçi Bostancı, Aytekin Tokmak, Dilek Şahin Uygur, Yasemin Taşçı
• Format: Article
• Language: English
• Published: Galenos Yayinevi 2018-09-01
• Series: Haseki Tıp Bülteni
• Subjects: Myoma uteri; infertility; clinical pregnancy; myomectomy; maternal age
• Online Access: http://www.hasekidergisi.com/archives/archive-detail/article-preview/factors-nfluencing-clinical-pregnancy-rates-after-/19660

Aim:To determine the clinical pregnancy rates after myomectomy in infertile women who underwent surgery due to myoma uteri and to investigate the clinical factors affecting outcomes.Methods:This retrospective single-centered study included infertile patients who underwent intramural and/or subserousal uterine myomectomy in the infertility clinic at our hospital between February 2012 and October 2014. Data were obtained from the hospital records and patients’ files. Age, body mass index, physical features of myomas (diameter, number, structure, and location), surgical treatment methods used and postoperative pregnancy status were recorded for each patient separately.Results:A total of 211 infertile women who met the inclusion criteria for this study and who underwent myomectomy due to myoma uteri were included. The mean myoma diameter was 7.3±4.4 cm and intramural tumors (49.8%) were the most commonly observed type. Laparoscopic myomectomy was performed in 186 patients (88.1%) and laparoscopic in 25 patients (11.9%). The clinical pregnancy rate was calculated as 19.9% (42/211), while 28.6% (12/42) of pregnancies resulted in live birth and 71.4% (30/42) in spontaneous abortion. The mean age of the pregnant and non-pregnant patients was 33.2±5.6 and 36.8±5.8 years, respectively. The mean body mass index was 25.9±3.5 and 28.8±4.8 kg/m2, respectively (p<0.001). There was no statistically significant difference between the groups in terms of myoma diameter, number, myometrial location, uterine location, and operation method (p>0.05).Conclusion:The most important factors for predicting pregnancy in patients who undergo surgery due to myoma and infertility are female age and body mass index. It seems that myoma diameter, number, myometrial location, uterine location and method of surgery are not significant factors in predicting pregnancy.