Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus

Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus

<p>Abstract</p> <p>Background</p> <p>Neuroinflammation plays an important role in cerebral ischemia/reperfusion (I/R) injury. The P2X7 receptor (P2X7R) has been reported to be involved in the inflammatory response of many central nervous system diseases. However, the ro...

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Bibliographic Details
Main Authors: Chu Ketan, Yin Bo, Wang Jingye, Peng Guoping, Liang Hui, Xu Ziqi, Du Yue, Fang Marong, Xia Qiang, Luo Benyan
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Journal of Neuroinflammation
Subjects:
P2X7 receptor
Ischemia/reperfusion injury
Inflammation
Microglia
Cytokine
Online Access:http://www.jnueroinflammation.com/content/9/1/69

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