A comparative study on 100% tca versus 88% phenol for the treatment of vitiligo

• Main Authors: Neerja Puri, Asha Puri
• Format: Article
• Language: English
• Published: Our Dermatology Online 2012-07-01
• Series: Nasza Dermatologia Online
• Subjects: vitiligo; repigmentation; melanocytes; pigment; TCA; phenol
• Online Access: http://www.odermatol.com/wp-content/uploads/file/2012%203/DOI-6.pdf

There are various medical and surgical modalities for the treatment of vitiligo. Surgical modalities are used in the patients who fail to respond to medical therapy. We selected thirty patients of stable vitiligo from the department of dermatology for the study. The patients were divided into two groups of 15 patients each. In Group I patients application of 100% TCA was done on the vitiliginous sites and in Group II patients 88% phenol was applied on the affected sites. Comparing the results of repigmentation in both the groups it was seen that marked pigmentation was seen in 66.6% patients in the TCA group and 80% in the Phenol group. Moderate pigmentation was seen in 13.3% patients in both the groups and mild pigmentation was seen in 20% patients in the TCA group and 6.6% in the Phenol group.