Random sequences rapidly evolve into de novo promoters
Bacterial promoters initiate gene transcription and have distinct sequence features. Here, the authors show that random sequences that contain no information are just on the verge of functioning as promoters in Escherichia coli.
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2018-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-04026-w |
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doaj-07f918e84cf940cca0a858222a05e078 |
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Article |
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doaj-07f918e84cf940cca0a858222a05e0782021-05-11T10:11:16ZengNature Publishing GroupNature Communications2041-17232018-04-019111010.1038/s41467-018-04026-wRandom sequences rapidly evolve into de novo promotersAvihu H. Yona0Eric J. Alm1Jeff Gore2Physics of Living Systems, Department of Physics, Massachusetts Institute of TechnologyDepartment of Biological Engineering, Massachusetts Institute of TechnologyPhysics of Living Systems, Department of Physics, Massachusetts Institute of TechnologyBacterial promoters initiate gene transcription and have distinct sequence features. Here, the authors show that random sequences that contain no information are just on the verge of functioning as promoters in Escherichia coli.https://doi.org/10.1038/s41467-018-04026-w |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Avihu H. Yona Eric J. Alm Jeff Gore |
| spellingShingle |
Avihu H. Yona Eric J. Alm Jeff Gore Random sequences rapidly evolve into de novo promoters Nature Communications |
| author_facet |
Avihu H. Yona Eric J. Alm Jeff Gore |
| author_sort |
Avihu H. Yona |
| title |
Random sequences rapidly evolve into de novo promoters |
| title_short |
Random sequences rapidly evolve into de novo promoters |
| title_full |
Random sequences rapidly evolve into de novo promoters |
| title_fullStr |
Random sequences rapidly evolve into de novo promoters |
| title_full_unstemmed |
Random sequences rapidly evolve into de novo promoters |
| title_sort |
random sequences rapidly evolve into de novo promoters |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2018-04-01 |
| description |
Bacterial promoters initiate gene transcription and have distinct sequence features. Here, the authors show that random sequences that contain no information are just on the verge of functioning as promoters in Escherichia coli. |
| url |
https://doi.org/10.1038/s41467-018-04026-w |
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AT avihuhyona randomsequencesrapidlyevolveintodenovopromoters AT ericjalm randomsequencesrapidlyevolveintodenovopromoters AT jeffgore randomsequencesrapidlyevolveintodenovopromoters |
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