Protective Effect of Prolactin against Methylmercury-Induced Mutagenicity and Cytotoxicity on Human Lymphocytes

Protective Effect of Prolactin against Methylmercury-Induced Mutagenicity and Cytotoxicity on Human Lymphocytes

Mercury exhibits cytotoxic and mutagenic properties as a result of its effect on tubulin. This toxicity mechanism is related to the production of free radicals that can cause DNA damage. Methylmercury (MeHg) is one of the most toxic of the mercury compounds. It accumulates in the aquatic food chain,...

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Bibliographic Details
Main Authors: Liz Carmem Silva-Pereira, Carlos Alberto Machado da Rocha, Luiz Raimundo Campos da Silva e Cunha, Edmar Tavares da Costa, Ana Paula Araújo Guimarães, Thais Brilhante Pontes, Domingos Luiz Wanderley Picanço Diniz, Mariana Ferreira Leal, Caroline Aquino Moreira-Nunes, Rommel Rodríguez Burbano
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:International Journal of Environmental Research and Public Health
Subjects:
methylmercury
prolactin
mutagenicity
mitotic index
Online Access:http://www.mdpi.com/1660-4601/11/9/9822

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