Uremic Toxins and Lipases in Haemodialysis: A Process of Repeated Metabolic Starvation

Severe kidney disease results in retention of uremic toxins that inhibit key enzymes for lipid breakdown such as lipoprotein lipase (LPL) and hepatic lipase (HL). For patients in haemodialysis (HD) and peritoneal dialysis (PD) the LPL activity is only about half of that of age and gender matched con...

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Bibliographic Details
Main Author: Bernd Stegmayr
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/6/5/1505

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