Computational Selection of RNA Aptamer against Angiopoietin-2 and Experimental Evaluation

Angiogenesis plays a decisive role in the growth and spread of cancer and angiopoietin-2 (Ang2) is in the spotlight of studies for its unique role in modulating angiogenesis. The aim of this study was to introduce a computational simulation approach to screen aptamers with high binding ability for A...

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Bibliographic Details
Main Authors: Wen-Pin Hu, Jangam Vikram Kumar, Chun-Jen Huang, Wen-Yih Chen
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/658712

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