Computational Selection of RNA Aptamer against Angiopoietin-2 and Experimental Evaluation
Angiogenesis plays a decisive role in the growth and spread of cancer and angiopoietin-2 (Ang2) is in the spotlight of studies for its unique role in modulating angiogenesis. The aim of this study was to introduce a computational simulation approach to screen aptamers with high binding ability for A...
Main Authors: | Wen-Pin Hu, Jangam Vikram Kumar, Chun-Jen Huang, Wen-Yih Chen |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2015-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2015/658712 |
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