Tanshinone II A Attenuates TNF-α-Induced Expression of VCAM-1 and ICAM-1 in Endothelial Progenitor Cells by Blocking Activation of NF-κB

Tanshinone II A Attenuates TNF-α-Induced Expression of VCAM-1 and ICAM-1 in Endothelial Progenitor Cells by Blocking Activation of NF-κB

Background/Aims: Tanshinone IIA (Tan IIA) is effective in the treatment of inflammation and atherosclerosis. The adhesion of inflammatory cells to vascular endothelium plays important role in atherogenic processes. This study examined the effects of Tan IIA on expression of adhesion molecules in tum...

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Bibliographic Details
Main Authors: Jin-Xiu Yang, Yan-Yun Pan, Jun-Hua Ge, Bin Chen, Wei Mao, Yuan-Gang Qiu, Xing-Xiang Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Tumor necrosis factor-α
Adhesion molecule
Endothelial progenitor cell
Nuclear factor κB
Tanshinone IIA
Online Access:http://www.karger.com/Article/FullText/452537

Internet

http://www.karger.com/Article/FullText/452537

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