Calotropis gigantea extract induces apoptosis through extrinsic/intrinsic pathways and reactive oxygen species generation in A549 and NCI-H1299 non-small cell lung cancer cells

Calotropis gigantea extract induces apoptosis through extrinsic/intrinsic pathways and reactive oxygen species generation in A549 and NCI-H1299 non-small cell lung cancer cells

Abstract Background Calotropis gigantea (CG) is a tall and waxy flower that is used as a traditional remedy for fever, indigestion, rheumatism, leprosy, and leukoderma. However, the precise mechanisms of its anticancer effects have not yet been examined in human non-small cell lung cancer (NSCLC) ce...

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Bibliographic Details
Main Authors: Jiyon Lee, Hui-Ju Jang, Hyunwoo Chun, Thu-Huyen Pham, Yesol Bak, Jong-Woon Shin, Hang Jin, Yong-In Kim, Hyung Won Ryu, Sei Ryang Oh, Do-Young Yoon
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Calotropis gigantea
Non-small cell lung cancer cell
Anti-cancer
Apoptosis
ROS
Online Access:http://link.springer.com/article/10.1186/s12906-019-2561-1

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