Diverse functions of homologous actin isoforms are defined by their nucleotide, rather than their amino acid sequence
β‐ and γ‐cytoplasmic actin are nearly indistinguishable in their amino acid sequence, but are encoded by different genes that play non‐redundant biological roles. The key determinants that drive their functional distinction are unknown. Here, we tested the hypothesis that β- and γ-actin functions ar...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-12-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/31661 |