Historical and Clinical Experiences of Gene Therapy  for Solid Cancers in China

Based on the theoretical and clinical development of modern medicines, gene therapy has been a promising treatment strategy for cancer and other diseases. The practice of gene therapy is nearly 27 years old, since the first authorized gene transfer study took place at the National Institute of Healt...

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Bibliographic Details
Main Authors: Bo Li, Ning Gao, Zhuang Zhang, Qian‐Ming Chen, Long‐Jiang Li, Yi Li
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Genes
Subjects:
Online Access:http://www.mdpi.com/2073-4425/8/3/85
Description
Summary:Based on the theoretical and clinical development of modern medicines, gene therapy has been a promising treatment strategy for cancer and other diseases. The practice of gene therapy is nearly 27 years old, since the first authorized gene transfer study took place at the National Institute of Health in 1989. However, gene therapy was not readily adopted worldwide, until recently. Several gene therapy clinical trials have been carried out in China since 1998, and medical research in China has flourished. In this report, we review the history of gene therapy in China, focusing on treatment protocol, the administration cycle, dosage calculation, and the evaluation of therapeutic effects, in order to provide more information for the additional development of this promising treatment strategy.
ISSN:2073-4425