Inhibition of Caspase-2 Translation by the mRNA Binding Protein HuR: A Novel Path of Therapy Resistance in Colon Carcinoma Cells?

An increased expression and cytoplasmic abundance of the ubiquitous RNA binding protein human antigen R (HuR) is critically implicated in the dysregulated control of post-transcriptional gene expression during colorectal cancer development and is frequently associated with a high grade of malignancy...

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Bibliographic Details
Main Authors: Wolfgang Eberhardt, Usman Nasrullah, Kristina Haeussler
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/8/797