Molecular and Mechanical Mechanisms of Calcification Pathology Induced by Bicuspid Aortic Valve Abnormalities

Molecular and Mechanical Mechanisms of Calcification Pathology Induced by Bicuspid Aortic Valve Abnormalities

Bicuspid aortic valve (BAV) is a congenital defect affecting 1–2% of the general population that is distinguished from the normal tricuspid aortic valve (TAV) by the existence of two, rather than three, functional leaflets (or cusps). BAV presents in different morphologic phenotypes based on the con...

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Bibliographic Details
Main Authors: Hail B. Kazik, Harkamaljot S. Kandail, John F. LaDisa, Joy Lincoln
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
hemodynamic
biomechanic
calcific aortic valve disease (CAVD)
wall shear stress
fluid-structure interaction simulation
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.677977/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2021.677977/full

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