Alteration of Tremor Dominant and Postural Instability Gait Difficulty Subtypes During the Progression of Parkinson's Disease: Analysis of the PPMI Cohort

Alteration of Tremor Dominant and Postural Instability Gait Difficulty Subtypes During the Progression of Parkinson's Disease: Analysis of the PPMI Cohort

Background: Classifying PD into tremor dominant (TD) and postural instability gait difficulty (PIGD) subtypes may have several limitations, such as its diagnostic inconsistency and inability to reflect disease stage. In this study, we investigated the patterns of progression and dopaminergic denerva...

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Bibliographic Details
Main Authors: Jeong Won Lee, Yoo Sung Song, Hyeyun Kim, Bon D. Ku, Won Woo Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Neurology
Subjects:
Parkinson's disease
tremor dominant
postural instability gait difficulty
PPMI
I-123 FP-CIT SPECT
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00471/full

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