Ocular administration of acetazolamide microsponges in situ gel formulations

In the present work, the antiglaucoma drug, acetazolamide, was formulated as microsponges in situ gel for ocular drug delivery aiming an improved therapeutic efficacy and reduction in the systemic side effects of oral acetazolamide. The microsponges were prepared by the quasi emulsion solvent diffus...

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Bibliographic Details
Main Authors: Manar M. Obiedallah, A.M. Abdel-Mageed, Tahani H. Elfaham
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016418300057