SARS-CoV-2-Associated Obliterative Arteritis Causing Massive Testicular Infarction

SARS-CoV-2-Associated Obliterative Arteritis Causing Massive Testicular Infarction

A 26-year-old man with symptomatic SARS-CoV-2 infection developed a sudden-onset acute testicular pain. The echo-doppler images showed massive testicular infarction, so orchiectomy was performed. On gross examination, the surgical specimen showed complete testicular necrosis and diffuse thickening o...

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Bibliographic Details
Main Authors: Dámaso Parrón, Ane Gartzia, Ane M. Iturregui, Igone Imaz, Claudia Manini, Jorge García-Olaverri, José I. López
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Clinics and Practice
Subjects:
SARS-CoV-2
COVID-19
arteritis
pathology
testicular infarction
Online Access:https://www.mdpi.com/2039-7283/11/2/37
Description
Summary:A 26-year-old man with symptomatic SARS-CoV-2 infection developed a sudden-onset acute testicular pain. The echo-doppler images showed massive testicular infarction, so orchiectomy was performed. On gross examination, the surgical specimen showed complete testicular necrosis and diffuse thickening of the testicular coverings. Under the microscope, a severe obliterative arteritis was evidenced. SARS-CoV-2 spike antibody was detected by immunohistochemistry in the arterial endothelium. Electron microscopy displayed intracytoplasmic spiky viral particles in endothelial cells. The patient was treated with corticoids and was asymptomatic at last contact.
ISSN:2039-7283

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