Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine

Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine

In pancreatic cancer, the epigenomic landscape can strongly impact the disease phenotype. Here, the authors discuss recent advances in our understanding of pancreatic cancer epigenomics, and how this knowledge can integrate with precision medicine approaches in this lethal disease.

Bibliographic Details
Main Authors: Gwen Lomberk, Nelson Dusetti, Juan Iovanna, Raul Urrutia
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11812-7
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spelling doaj-0784c10024e34076bcbf2a0a39e6dc2f2021-05-11T12:11:29ZengNature Publishing GroupNature Communications2041-17232019-08-0110111010.1038/s41467-019-11812-7Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicineGwen Lomberk0Nelson Dusetti1Juan Iovanna2Raul Urrutia3Division of Research, Department of Surgery and the Genomic Sciences and Precision Medicine Center (GSPMC), Medical College of WisconsinCentre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de LuminyCentre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de LuminyDivision of Research, Department of Surgery and the Genomic Sciences and Precision Medicine Center (GSPMC), Medical College of WisconsinIn pancreatic cancer, the epigenomic landscape can strongly impact the disease phenotype. Here, the authors discuss recent advances in our understanding of pancreatic cancer epigenomics, and how this knowledge can integrate with precision medicine approaches in this lethal disease.https://doi.org/10.1038/s41467-019-11812-7
collection DOAJ
language English
format Article
sources DOAJ
author Gwen Lomberk
Nelson Dusetti
Juan Iovanna
Raul Urrutia
spellingShingle Gwen Lomberk
Nelson Dusetti
Juan Iovanna
Raul Urrutia
Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine
Nature Communications
author_facet Gwen Lomberk
Nelson Dusetti
Juan Iovanna
Raul Urrutia
author_sort Gwen Lomberk
title Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine
title_short Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine
title_full Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine
title_fullStr Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine
title_full_unstemmed Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine
title_sort emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2019-08-01
description In pancreatic cancer, the epigenomic landscape can strongly impact the disease phenotype. Here, the authors discuss recent advances in our understanding of pancreatic cancer epigenomics, and how this knowledge can integrate with precision medicine approaches in this lethal disease.
url https://doi.org/10.1038/s41467-019-11812-7
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AT nelsondusetti emergingepigenomiclandscapesofpancreaticcancerintheeraofprecisionmedicine
AT juaniovanna emergingepigenomiclandscapesofpancreaticcancerintheeraofprecisionmedicine
AT raulurrutia emergingepigenomiclandscapesofpancreaticcancerintheeraofprecisionmedicine
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