Aberrant BMP2 Signaling in Patients Diagnosed with Osteoporosis

The most common bone disease in humans is osteoporosis (OP). Current therapeutics targeting OP have several negative side effects. Bone morphogenetic protein 2 (BMP2) is a potent growth factor that is known to activate both osteoblasts and osteoclasts. It completes these actions through both SMAD-de...

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Bibliographic Details
Main Authors: Hilary W. Durbano, Daniel Halloran, John Nguyen, Victoria Stone, Sean McTague, Mark Eskander, Anja Nohe
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
CK2
Online Access:https://www.mdpi.com/1422-0067/21/18/6909